Role of B cells in vaccine-induced immunity against coccidioidomycosis.
نویسندگان
چکیده
We investigated secondary immunity against coccidioidomycosis by using gene expression microarrays. Surprisingly, a high percentage of B-cell-related genes were associated with protective immunity. A functional confirmation of the importance of B cells against coccidioidomycosis was achieved by demonstrating that vaccination was not fully protective in B-cell-deficient MuMT mice.
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عنوان ژورنال:
- Infection and immunity
دوره 73 10 شماره
صفحات -
تاریخ انتشار 2005